Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

BACKGROUND: The Fat mass and obesity gene (FTO) has been identified through genome wide association studies as an important genetic factor contributing to a higher body mass index (BMI). However, the molecular context in which this effect is mediated has yet to be determined. We investigated the pot...

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Detalhes bibliográficos
Main Authors: Rask-Andersen, Mathias, Almén, Markus Sällman, Olausen, Hans R, Olszewski, Pawel K, Eriksson, Jenny, Chavan, Rohit A, Levine, Allen S, Fredriksson, Robert, Schiöth, Helgi B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248879/
https://ncbi.nlm.nih.gov/pubmed/22087873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-117
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