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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
To fulfill the bioenergetic and biosynthetic demand of proliferation, T cells reprogram their metabolic pathways from fatty acid β-oxidation and pyruvate oxidation via the TCA cycle to the glycolytic, pentose-phosphate, and glutaminolytic pathways. Two of the top-ranked candidate transcription facto...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248798/ https://ncbi.nlm.nih.gov/pubmed/22195744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.09.021 |
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