The role of nuclear lamin B1 in cell proliferation and senescence

Nuclear lamin B1 (LB1) is a major structural component of the nucleus that appears to be involved in the regulation of many nuclear functions. The results of this study demonstrate that LB1 expression in WI-38 cells decreases during cellular senescence. Premature senescence induced by oncogenic Ras...

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Main Authors: Shimi, Takeshi, Butin-Israeli, Veronika, Adam, Stephen A., Hamanaka, Robert B., Goldman, Anne E., Lucas, Catherine A., Shumaker, Dale K., Kosak, Steven T., Chandel, Navdeep S., Goldman, Robert D.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248680/
https://ncbi.nlm.nih.gov/pubmed/22155925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.179515.111
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