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Advantages of a Mechanistic Codon Substitution Model for Evolutionary Analysis of Protein-Coding Sequences

BACKGROUND: A mechanistic codon substitution model, in which each codon substitution rate is proportional to the product of a codon mutation rate and the average fixation probability depending on the type of amino acid replacement, has advantages over nucleotide, amino acid, and empirical codon subs...

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Detalhes bibliográficos
Autor principal: Miyazawa, Sanzo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248416/
https://ncbi.nlm.nih.gov/pubmed/22220197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028892
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