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Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiers
BACKGROUND: Maturation inhibitors such as Bevirimat are a new class of antiretroviral drugs that hamper the cleavage of HIV-1 proteins into their functional active forms. They bind to these preproteins and inhibit their cleavage by the HIV-1 protease, resulting in non-functional virus particles. Nev...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248369/ https://ncbi.nlm.nih.gov/pubmed/22082002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-4-26 |
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