Pathogenesis and Treatment of Thrombohemorrhagic Diathesis in Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is a distinct subtype of myeloid leukemia characterized by t(15;17) chromosomal translocation, which involves the retinoic acid receptor-alpha (RAR-alpha). APL typically presents with a life-threatening hemorrhagic diathesis. Before the introduction of all-trans re...

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Bibliographic Details
Main Authors: Falanga, Anna, Russo, Laura, Tartari, Carmen J
Format: Artigo
Language:Inglês
Published: Università Cattolica del Sacro Cuore 2011
Subjects:
Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248345/
https://ncbi.nlm.nih.gov/pubmed/22220265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2011.068
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