Gelsolin Associates with the N Terminus of Syntaxin 4 to Regulate Insulin Granule Exocytosis

The plasma membrane soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) protein syntaxin (Syn)4 is required for biphasic insulin secretion, although how it regulates each phase remains unclear. In a screen to identify new Syn4-interacting factors, the calcium-activated F-actin-seve...

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Bibliographic Details
Main Authors: Kalwat, Michael A., Wiseman, Dean A., Luo, Wei, Wang, Zhanxiang, Thurmond, Debbie C.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248323/
https://ncbi.nlm.nih.gov/pubmed/22108804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1112
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