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Epoxyeicosatrienoic acids: a double-edged sword in cardiovascular diseases and cancer

Epoxyeicosatrienoic acids (EETs) generated from arachidonic acid by cytochrome P450 (CYP) epoxygenases have beneficial effects in certain cardiovascular and kidney diseases. Hence, great efforts have been made to develop drugs targeting the EET pathway. Some of these agents are currently under evalu...

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Detalhes bibliográficos
Main Authors: Wang, Dingzhi, DuBois, Raymond N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248310/
https://ncbi.nlm.nih.gov/pubmed/22182836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61453
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