Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

Epoxyeicosatrienoic acids (EETs) are small molecules produced by cytochrome P450 epoxygenases. They are lipid mediators that act as autocrine or paracrine factors to regulate inflammation and vascular tone. As a result, drugs that raise EET levels are in clinical trials for the treatment of hyperten...

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Detalhes bibliográficos
Main Authors: Panigrahy, Dipak, Edin, Matthew L., Lee, Craig R., Huang, Sui, Bielenberg, Diane R., Butterfield, Catherine E., Barnés, Carmen M., Mammoto, Akiko, Mammoto, Tadanori, Luria, Ayala, Benny, Ofra, Chaponis, Deviney M., Dudley, Andrew C., Greene, Emily R., Vergilio, Jo-Anne, Pietramaggiori, Giorgio, Scherer-Pietramaggiori, Sandra S., Short, Sarah M., Seth, Meetu, Lih, Fred B., Tomer, Kenneth B., Yang, Jun, Schwendener, Reto A., Hammock, Bruce D., Falck, John R., Manthati, Vijaya L., Ingber, Donald E., Kaipainen, Arja, D’Amore, Patricia A., Kieran, Mark W., Zeldin, Darryl C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248288/
https://ncbi.nlm.nih.gov/pubmed/22182838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58128
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