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Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1

Haem oxygenase-1 (HO-1) is increasingly regarded as a pro-tumoral target in the treatment of human cancers. Currently, little is known about HO-1 and its role in human acute myeloid leukaemia (AML) to regulate apoptosis in response to chemotherapy. Recently, we showed that HO-1 protects AML samples...

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Autors principals: Heasman, Sally-Anne, Zaitseva, Lyubov, Bowles, Kristian M., Rushworth, Stuart A., MacEwan, David J.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248221/
https://ncbi.nlm.nih.gov/pubmed/21911919
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