The requirement of p53 for maintaining chromosomal stability during tetraploidization

Tetraploidization is believed to promote genome instability and tumorigenesis. Whether tetraploids per se are intrinsically unstable and transforming remain incompletely understood. In this report, tetraploidization was induced with cell fusion using mouse fibroblasts. Due to the unequal segregation...

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Bibliografiska uppgifter
Huvudupphovsmän: Ho, Chui Chui, Hau, Pok Man, Marxer, Miriam, Poon, Randy Y.C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2010
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248137/
https://ncbi.nlm.nih.gov/pubmed/21317454
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