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A novel screen using the Reck tumor suppressor gene promoter detects both conventional and metastasis-suppressing anticancer drugs

The membrane-anchored matrix metalloproteinase-regulator RECK is often down-regulated in various types of cancers; the levels of residual RECK in resected tumors often correlate with better prognosis. Forced expression of RECK in cancer cells suppresses tumor angiogenesis, invasion, and metastasis i...

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Main Authors: Murai, Ryuya, Yoshida, Yoko, Muraguchi, Teruyuki, Nishimoto, Emi, Morioka, Yoko, Kitayama, Hitoshi, Kondoh, Shinae, Kawazoe, Yoshinori, Hiraoka, Masahiro, Uesugi, Motonari, Noda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248105/
https://ncbi.nlm.nih.gov/pubmed/21304177
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