The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs

The membrane-anchored metalloproteinase-regulator RECK has been characterized as a tumor suppressor. Here we report that mice with reduced Reck-expression show limb abnormalities including right-dominant, forelimb-specific defects in postaxial skeletal elements. The forelimb buds of low-Reck mutants...

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書誌詳細
主要な著者: Yamamoto, Mako, Matsuzaki, Tomoko, Takahashi, Rei, Adachi, Eijiro, Maeda, Yasuhiro, Yamaguchi, Sachiyo, Kitayama, Hitoshi, Echizenya, Michiko, Morioka, Yoko, Alexander, David B., Yagi, Takeshi, Itohara, Shigeyoshi, Nakamura, Takashi, Akiyama, Haruhiko, Noda, Makoto
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507216/
https://ncbi.nlm.nih.gov/pubmed/23213437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.2012638
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