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Identification of Respective Lysine Donor and Glutamine Acceptor Sites Involved in Factor XIIIa-catalyzed Fibrin α Chain Cross-linking

Factor XIIIa-catalyzed ϵ-(γ-glutamyl)-lysyl bonds between glutamine and lysine residues on fibrin α and γ chains stabilize the fibrin clot and protect it from mechanical and proteolytic damage. The cross-linking of γ chains is known to involve the reciprocal linkages between Gln(398) and Lys(406). I...

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Autor Principal: Wang(汪, Weixun, 炜迅)
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248016/
https://ncbi.nlm.nih.gov/pubmed/22030394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297119
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