Phosphorylation of PhoP Protein Plays Direct Regulatory Role in Lipid Biosynthesis of Mycobacterium tuberculosis

Mycobacterium tuberculosis PhoP is essential for virulence and intracellular growth of the tubercle bacilli. Genetic evidence suggests that PhoP regulates complex lipid biosynthesis, and absence of some of these lipid molecules in a phoP mutant partly accounts for its attenuated growth in macrophage...

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Hlavní autoři: Goyal, Rajni, Das, Arijit Kumar, Singh, Ranjeet, Singh, Pradip K., Korpole, Suresh, Sarkar, Dibyendu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247998/
https://ncbi.nlm.nih.gov/pubmed/22072719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307447
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