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Nuclear Factor κB Subunits RelB and cRel Negatively Regulate Toll-like Receptor 3-mediated β-Interferon Production via Induction of Transcriptional Repressor Protein YY1

The induction of β-interferon (IFN-β) is a key anti-viral response to infection by RNA viruses. Virus-induced expression of IFN-β requires the co-operative action of the transcription factors IRF-3/7, NF-κB, and ATF-2/c-Jun on the IFN-β promoter leading to the orderly recruitment of chromatin remode...

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Detalhes bibliográficos
Main Authors: Siednienko, Jakub, Maratha, Ashwini, Yang, Shuo, Mitkiewicz, Malgorzata, Miggin, Sinéad M., Moynagh, Paul N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247990/
https://ncbi.nlm.nih.gov/pubmed/22065573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.250894
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