Exogenous Ceramide-1-phosphate Reduces Lipopolysaccharide (LPS)-mediated Cytokine Expression

Toll-like receptor 4 (TLR4) is a component of the innate immune system that recognizes a diverse group of molecular structures, such as lipopolysaccharide (LPS) from Gram-negative bacteria. TLR4 signaling ultimately leads to activation of the transcription factor, nuclear factor κB (NF-κB), and the...

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Main Authors: Hankins, Jody L., Fox, Todd E., Barth, Brian M., Unrath, Kellee A., Kester, Mark
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247944/
https://ncbi.nlm.nih.gov/pubmed/22065582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264010
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