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An improved classification of G-protein-coupled receptors using sequence-derived features
BACKGROUND: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structures of GPCRs are largely unavailable; however, a large number of GPCR primary sequences are known. To facilitate the ident...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3247138/ https://ncbi.nlm.nih.gov/pubmed/20696050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-420 |
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