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FragSeq: transcriptome-wide RNA structure probing using high-throughput sequencing
Previous efforts to determine structures of non-coding RNA (ncRNA) probed only one RNA at a time with enzymes and chemicals, using gel electrophoresis to identify reactive positions. To accelerate RNA structure inference, we have developed FragSeq, a high-throughput RNA structure probing method that...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3247016/ https://ncbi.nlm.nih.gov/pubmed/21057495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1529 |
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