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Differential Effects of Trisomy on Brain Shape and Volume in Related Aneuploid Mouse Models
Down syndrome (DS) results from inheritance of three copies of human chromosome 21 (Hsa21). Individuals with DS have a significantly smaller brain size overall and a disproportionately small cerebellum. The small cerebellum is seen in Ts65Dn mice, which have segmental trisomy for orthologs of about...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246902/ https://ncbi.nlm.nih.gov/pubmed/17431903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.31721 |
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