Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells

BACKGROUND AND PURPOSE: Anti-angiogenic agents have recently become one of the major adjuvants for cancer therapy. A cyclopeptide, RA-V, has been shown to have anti-tumour activities. Its in vitro anti-angiogenic activities were evaluated in the present study, and the underlying mechanisms were also...

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Главные авторы: Yue, Grace GL, Fan, Jun-Ting, Lee, Julia KM, Zeng, Guang-Zhi, Ho, Tina WF, Fung, Kwok-Pui, Leung, Ping-Chung, Tan, Ning-Hua, Lau, Clara BS
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2011
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Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246713/
https://ncbi.nlm.nih.gov/pubmed/21518338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01458.x
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