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Tryptanthrin Inhibits Angiogenesis by Targeting the VEGFR2-Mediated ERK1/2 Signalling Pathway

Angiogenesis is a key step for tumour growth and metastasis, and anti-angiogenesis has been proposed as an important strategy for cancer therapy. Tryptanthrin is a weakly basic alkaloid isolated from the dried roots of medicinal indigo plants and has been shown to possess anti-tumour activities on v...

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Detalhes bibliográficos
Main Authors: Liao, Xuemei, Zhou, Xuelin, Mak, Nai-ki, Leung, Kwok-nam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864955/
https://ncbi.nlm.nih.gov/pubmed/24358167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082294
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