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Catechol-O-Methyltransferase Val158Met Polymorphism Associates with Individual Differences in Sleep Physiologic Responses to Chronic Sleep Loss

BACKGROUND: The COMT Val158Met polymorphism modulates cortical dopaminergic catabolism, and predicts individual differences in prefrontal executive functioning in healthy adults and schizophrenic patients, and associates with EEG differences during sleep loss. We assessed whether the COMT Val158Met...

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Autors principals: Goel, Namni, Banks, Siobhan, Lin, Ling, Mignot, Emmanuel, Dinges, David F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246458/
https://ncbi.nlm.nih.gov/pubmed/22216231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029283
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