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PER3 Polymorphism Predicts Cumulative Sleep Homeostatic but Not Neurobehavioral Changes to Chronic Partial Sleep Deprivation

BACKGROUND: The variable number tandem repeat (VNTR) polymorphism 5-repeat allele of the circadian gene PERIOD3 (PER3(5/5)) has been associated with cognitive decline at a specific circadian phase in response to a night of total sleep deprivation (TSD), relative to the 4-repeat allele (PER3(4/4)). P...

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Autors principals: Goel, Namni, Banks, Siobhan, Mignot, Emmanuel, Dinges, David F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689932/
https://ncbi.nlm.nih.gov/pubmed/19516903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005874
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