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Regulation of Insulin Gene Transcription by Multiple Histone Acetyltransferases
Glucose-stimulated insulin gene transcription is mainly regulated by a 340-bp promoter region upstream of the transcription start site by beta-cell-enriched transcription factors Pdx-1, MafA, and NeuroD1. Previous studies have shown that histone H4 hyperacetylation is important for acute up-regulati...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Mary Ann Liebert, Inc.
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246418/ https://ncbi.nlm.nih.gov/pubmed/21774670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2011.1336 |
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