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Using Infrared Spectroscopy of Cyanylated Cysteine to Map Membrane Binding Structure and Orientation of the Hybrid Antimicrobial Peptide CM15

The synthetic antimicrobial peptide CM15, a hybrid of N-terminal sequences from cecropin and melittin peptides, has been shown to be extremely potent. Its mechanism of action has been speculated to involve pore formation based on prior site-directed spin labeling studies. This study examines four si...

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Detalhes bibliográficos
Main Authors: Alfieri, Katherine N., Vienneau, Alice R., Londergan, Casey H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246368/
https://ncbi.nlm.nih.gov/pubmed/22103476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200903p
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