Epac enhances excitation-transcription coupling in cardiac myocytes

Epac is a guanine nucleotide exchange protein that is directly activated by cAMP, but whose cardiac cellular functions remain unclear. It is important to understand cardiac Epac signaling, because it is activated in parallel to classical cAMP-dependent signaling via protein kinase A. In addition to...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pereira, Laetitia, Ruiz-Hurtado, Gema, Morel, Eric, Laurent, Anne-Coline, Métrich, Mélanie, Domínguez, Alejandro, Lauton, Sandra, Lucas, Alexandre, Benitah, Jean-Pierre, Bers, Donald M., Lezoualc’h, Frank, Gómez, Ana M.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246099/
https://ncbi.nlm.nih.gov/pubmed/22056318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.10.016
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