Epac enhances excitation-transcription coupling in cardiac myocytes

Epac is a guanine nucleotide exchange protein that is directly activated by cAMP, but whose cardiac cellular functions remain unclear. It is important to understand cardiac Epac signaling, because it is activated in parallel to classical cAMP-dependent signaling via protein kinase A. In addition to...

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Detalhes bibliográficos
Main Authors: Pereira, Laetitia, Ruiz-Hurtado, Gema, Morel, Eric, Laurent, Anne-Coline, Métrich, Mélanie, Domínguez, Alejandro, Lauton, Sandra, Lucas, Alexandre, Benitah, Jean-Pierre, Bers, Donald M., Lezoualc’h, Frank, Gómez, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246099/
https://ncbi.nlm.nih.gov/pubmed/22056318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.10.016
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