Vitamin A and immune regulation: Role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance

The vitamin A (VA) metabolite all-trans retinoic acid (RA) plays a key role in mucosal immune responses. RA is produced by gut-associated dendritic cells (DC), on which it also acts in a positive feedback loop to induce enzymes involved in its own synthesis. RA is required for generating gut-tropic...

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Hauptverfasser: Cassani, Barbara, Villablanca, Eduardo J., De Calisto, Jaime, Wang, Sen, Mora, J. Rodrigo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246074/
https://ncbi.nlm.nih.gov/pubmed/22120429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2011.11.001
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