Gut-tropic T Cells that Express Integrin α4β7 and CCR9 are Required for Induction of Oral Immune Tolerance in Mice

BACKGROUND & AIMS: Induction of oral immunological tolerance (OT) blocks proinflammatory responses to orally administered antigens; this approach might be used to treat autoimmune conditions. We investigated whether gut-tropic T cells that express the integrin α4β7 and the chemokine receptor CCR...

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Main Authors: Cassani, Barbara, Villablanca, Eduardo J., Quintana, Francisco J., Love, Paul E., Lacy-Hulbert, Adam, Blaner, William S., Sparwasser, Tim, Snapper, Scott B., Weiner, Howard L., Mora, J. Rodrigo
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222333/
https://ncbi.nlm.nih.gov/pubmed/21925467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.09.015
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