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Ketamine Activates Breathing and Abolishes the Coupling between Loss of Consciousness and Upper Airway Dilator Muscle Dysfunction

BACKGROUND: Procedural sedation is frequently performed in spontaneously breathing patients but hypnotics and opioids decrease respiratory drive and place the upper airway at risk for collapse. METHODS: In a randomized, controlled, cross-over, pharmaco-physiological study in 12 rats, we conducted ac...

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Detalhes bibliográficos
Main Authors: Eikermann, Matthias, Grosse-Sundrup, Martina, Zaremba, Sebastian, Henry, Mark E., Bittner, Edward A., Hoffmann, Ulrike, Chamberlin, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246073/
https://ncbi.nlm.nih.gov/pubmed/22108392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31823d010a
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