The Ventrolateral Preoptic Nucleus Is Not Required for Deep Isoflurane General Anesthesia

Neurons of the ventrolateral preoptic nucleus (VLPO) promote sleep and VLPO loss produces insomnia. Previous studies show that general anesthetics including isoflurane activate VLPO neurons, and may contribute to their sedative effects. However, it is not clear to what extent the activation of VLPO...

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Main Authors: Eikermann, Matthias, Vetrivelan, Ramalingam, Grosse-Sundrup, Martina, Henry, Mark E., Hoffmann, Ulrike, Yokota, Shigefumi, Saper, Clifford B., Chamberlin, Nancy L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215917/
https://ncbi.nlm.nih.gov/pubmed/22041226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.10.018
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