The Ventrolateral Preoptic Nucleus Is Not Required for Deep Isoflurane General Anesthesia

Neurons of the ventrolateral preoptic nucleus (VLPO) promote sleep and VLPO loss produces insomnia. Previous studies show that general anesthetics including isoflurane activate VLPO neurons, and may contribute to their sedative effects. However, it is not clear to what extent the activation of VLPO...

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Autores principales: Eikermann, Matthias, Vetrivelan, Ramalingam, Grosse-Sundrup, Martina, Henry, Mark E., Hoffmann, Ulrike, Yokota, Shigefumi, Saper, Clifford B., Chamberlin, Nancy L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215917/
https://ncbi.nlm.nih.gov/pubmed/22041226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.10.018
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