dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells

Double-stranded RNA (dsRNA) can enter different pathways in mammalian cells, including sequence-specific RNA interference (RNAi), sequence-independent interferon (IFN) response and editing by adenosine deaminases. To study the routing of dsRNA to these pathways in vivo, we used transgenic mice ubiqu...

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Bibliografske podrobnosti
Main Authors: Nejepinska, Jana, Malik, Radek, Filkowski, Jody, Flemr, Matyas, Filipowicz, Witold, Svoboda, Petr
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245926/
https://ncbi.nlm.nih.gov/pubmed/21908396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr702
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