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Dif1 is a DNA Damage Regulated Facilitator of Nuclear Import for Ribonucleotide Reductase

The control of dNTP concentrations is critical to the fidelity of DNA synthesis and repair. One level of regulation is through subcellular localization of ribonucleotide reductase. In S. cerevisiae, the small subunit, Rnr2-Rnr4, is nuclear while the large subunit, Rnr1, is cytoplasmic. In response t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Yang David, Wang, Jun, Stubbe, JoAnne, Elledge, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245869/
https://ncbi.nlm.nih.gov/pubmed/18851834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.08.018
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