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Proto-oncogene CT10-regulated kinase (CRK) is a pro-apoptotic transducer of endoplasmic reticulum stress

Excessive demands on the protein folding capacity of the endoplasmic reticulum (ER) cause irremediable ER stress and contribute to cell loss in a number of cell degenerative diseases, including type 2 diabetes and neurodegeneration(1,2). The signals communicating catastrophic ER damage to the mitoch...

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Detalles Bibliográficos
Main Authors: Austgen, Kathryn, Johnson, Emily T., Park, Tae-Ju, Curran, Tom, Oakes, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245775/
https://ncbi.nlm.nih.gov/pubmed/22179045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2395
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