Association of IL-10-Promoter Genetic Variants With the Rate of CD4 T-Cell Loss, IL-10 Plasma Levels, and Breadth of Cytotoxic T-Cell Lymphocyte Response During Chronic HIV-1 Infection

Background. Interleukin-10 (IL-10) is a potent immunoregulatory cytokine. IL-10-promoter polymorphisms have been shown to affect human immunodeficiency virus type 1 (HIV-1) clinical outcomes but the underlying mechanisms are poorly understood. Methods. We investigated the relationship between IL-10-...

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Main Authors: Naicker, Dshanta D., Wang, Bingxia, Losina, Elena, Zupkosky, Jennifer, Bryan, Susan, Reddy, Shabashini, Jaggernath, Manjeetha, Mokgoro, Mammekwa, Goulder, Philip J. R., Kaufmann, Daniel E., Ndung’u, Thumbi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
HIV/AIDS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245732/
https://ncbi.nlm.nih.gov/pubmed/22100578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cir811
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