Cargando...

The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography

Both crystallization and cryoprotection are often bottlenecks for high-resolution X-ray structure determination of macromolecules. Methylamine osmolytes are known stabilizers of protein structure. One such osmolyte, trimethylamine N-oxide (TMAO), has seen occasional use as an additive to improve mac...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Marshall, Haley, Venkat, Murugappan, Hti Lar Seng, Nang San, Cahn, Jackson, Juers, Douglas H.
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245723/
https://ncbi.nlm.nih.gov/pubmed/22194335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444911050360
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!