Urine TMPRSS2:ERG fusion transcript stratifies prostate cancer risk in men with elevated serum PSA

More than 1,000,000 men undergo prostate biopsy each year in the United States, most for “elevated” serum prostate specific antigen (PSA). Given the lack of specificity and unclear mortality benefit of PSA testing, methods to individualize management of elevated PSA are needed. Greater than 50% of P...

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Main Authors: Tomlins, Scott A., Aubin, Sheila M. J., Siddiqui, Javed, Lonigro, Robert J., Sefton-Miller, Laurie, Miick, Siobhan, Williamsen, Sarah, Hodge, Petrea, Meinke, Jessica, Blase, Amy, Penabella, Yvonne, Day, John R., Varambally, Radhika, Han, Bo, Wood, David, Wang, Lei, Sanda, Martin G., Rubin, Mark A., Rhodes, Daniel R., Hollenbeck, Brent, Sakamoto, Kyoko, Silberstein, Jonathan L., Fradet, Yves, Amberson, James B., Meyers, Stephanie, Palanisamy, Nallasivam, Rittenhouse, Harry, Wei, John T., Groskopf, Jack, Chinnaiyan, Arul M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245713/
https://ncbi.nlm.nih.gov/pubmed/21813756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3001970
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