A proteasome-dependent, TAP-independent pathway for cross-presentation of phagocytosed antigen

Major histocompatibility complex (MHC) class I cross-presentation is thought to involve two pathways, one of which depends on both the TAP transporters and the proteasome and the other on neither. We found that preincubation of TAP-deficient dendritic cells at low temperature increases the density o...

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Hlavní autoři: Merzougui, Nawel, Kratzer, Roland, Saveanu, Loredana, van Endert, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245693/
https://ncbi.nlm.nih.gov/pubmed/22037009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.203
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