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Analysis of substrate specificity of Schizosaccharomyces pombe Mag1 alkylpurine DNA glycosylase

DNA glycosylases specialized for the repair of alkylation damage must identify, with fine specificity, a diverse array of subtle modifications within DNA. The current mechanism involves damage sensing through interrogation of the DNA duplex, followed by more specific recognition of the target base i...

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Bibliografske podrobnosti
Main Authors: Adhikary, Suraj, Eichman, Brandt F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245690/
https://ncbi.nlm.nih.gov/pubmed/21960007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.189
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