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Single-cell copy number variation detection

Detection of chromosomal aberrations from a single cell by array comparative genomic hybridization (single-cell array CGH), instead of from a population of cells, is an emerging technique. However, such detection is challenging because of the genome artifacts and the DNA amplification process inhere...

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Autori principali: Cheng, Jiqiu, Vanneste, Evelyne, Konings, Peter, Voet, Thierry, Vermeesch, Joris R, Moreau, Yves
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245619/
https://ncbi.nlm.nih.gov/pubmed/21854607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-8-r80
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