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Three-dimensional modeling of chromatin structure from interaction frequency data using Markov chain Monte Carlo sampling
BACKGROUND: Long-range interactions between regulatory DNA elements such as enhancers, insulators and promoters play an important role in regulating transcription. As chromatin contacts have been found throughout the human genome and in different cell types, spatial transcriptional control is now vi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245522/ https://ncbi.nlm.nih.gov/pubmed/22026390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-414 |
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