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Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility

BACKGROUND: Cell migration plays an important role in many physiological and pathological processes, including immune cell chemotaxis and cancer metastasis. It is a coordinated process that involves dynamic changes in the actin cytoskeleton and its interplay with focal adhesions. At the leading edge...

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Autors principals: Wang, Wenqi, Liu, Yang, Liao, Kan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245448/
https://ncbi.nlm.nih.gov/pubmed/22078467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-12-49
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