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OOPHORECTOMY-INDUCED BONE LOSS IS ATTENUATED IN MAGP1-DEFICIENT MICE

Microfibril-associated glycoprotein-1 (MAGP1)(¶), together with the fibrillins, are constitutive components of vertebrate microfibrils. Mice deficient in MAGP1 (MAGP1Δ) develop progressive osteopenia and reduced whole-bone strength, and have elevated numbers of osteoclasts lining the bone surface. O...

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Autors principals: Craft, Clarissa S., Broekelmann, Thomas J., Zou, Wei, Chappel, Jean C., Teitelbaum, Steven L., Mecham, Robert P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245339/
https://ncbi.nlm.nih.gov/pubmed/21898536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23331
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