Global Analysis of DNA Methylation by Methyl-Capture Sequencing Reveals Epigenetic Control of Cisplatin Resistance in Ovarian Cancer Cell

Cisplatin resistance is one of the major reasons leading to the high death rate of ovarian cancer. Methyl-Capture sequencing (MethylCap-seq), which combines precipitation of methylated DNA by recombinant methyl-CpG binding domain of MBD2 protein with NGS, global and unbiased analysis of global DNA m...

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Detalhes bibliográficos
Main Authors: Yu, Wei, Jin, Chengmeng, Lou, Xiaoyan, Han, Xu, Li, Lisha, He, Yinghua, Zhang, Hongyu, Ma, Kelong, Zhu, Jingde, Cheng, Lihua, Lin, Biaoyang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245283/
https://ncbi.nlm.nih.gov/pubmed/22216282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029450
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