Alteration of Gene Expression Profile in Niemann-Pick Type C Mice Correlates with Tissue Damage and Oxidative Stress

BACKGROUND: Niemann-Pick type C disease (NPC) is a neurovisceral lipid storage disorder mainly characterized by unesterified cholesterol accumulation in lysosomal/late endosomal compartments, although there is also an important storage for several other kind of lipids. The main tissues affected by t...

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Hauptverfasser: Vázquez, Mary C., del Pozo, Talía, Robledo, Fermín A., Carrasco, Gonzalo, Pavez, Leonardo, Olivares, Felipe, González, Mauricio, Zanlungo, Silvana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245218/
https://ncbi.nlm.nih.gov/pubmed/22216111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028777
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