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Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1(fl/fl) mice

It has been reported that the intracellular antiapoptotic factor myeloid cell leukemia sequence 1 (Mcl-1) is required for mast cell survival in vitro, and that genetic manipulation of Mcl-1 can be used to delete individual hematopoietic cell populations in vivo. In the present study, we report the g...

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Autori principali: Lilla, Jennifer N., Chen, Ching-Cheng, Mukai, Kaori, BenBarak, Maya J., Franco, Christopher B., Kalesnikoff, Janet, Yu, Mang, Tsai, Mindy, Piliponsky, Adrian M., Galli, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245213/
https://ncbi.nlm.nih.gov/pubmed/22001390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-343962
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