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insomniac and Cullin-3 Regulate Sleep and Wakefulness in Drosophila
In a forward genetic screen in Drosophila, we have isolated insomniac, a mutant that severely reduces the duration and consolidation of sleep. Anatomically-restricted genetic manipulations indicate that insomniac functions within neurons to regulate sleep. insomniac expression does not oscillate in...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244879/ https://ncbi.nlm.nih.gov/pubmed/22196332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.12.003 |
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