B7-H1–Dependent Sex-Related Differences in Tumor Immunity and Immunotherapy Responses

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) are immunopathogenic in cancers by impeding tumor-specific immunity. B7-homologue 1 (B7-H1) (CD274) is a cosignaling molecule with pleiotropic effects, including hindering antitumor immunity. In this study, we demonstrate sex-dependent, B7-H1–dependen...

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Autores principales: Lin, Pei-Yi, Sun, Lishi, Thibodeaux, Suzanne R., Ludwig, Sara M., Vadlamudi, Ratna K., Hurez, Vincent J., Bahar, Rumana, Kious, Mark J., Livi, Carolina B., Wall, Shawna R., Chen, Lieping, Zhang, Bin, Shin, Tahiro, Curiel, Tyler J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244840/
https://ncbi.nlm.nih.gov/pubmed/20686128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000496
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