B7-H1–Dependent Sex-Related Differences in Tumor Immunity and Immunotherapy Responses

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) are immunopathogenic in cancers by impeding tumor-specific immunity. B7-homologue 1 (B7-H1) (CD274) is a cosignaling molecule with pleiotropic effects, including hindering antitumor immunity. In this study, we demonstrate sex-dependent, B7-H1–dependen...

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Detalhes bibliográficos
Main Authors: Lin, Pei-Yi, Sun, Lishi, Thibodeaux, Suzanne R., Ludwig, Sara M., Vadlamudi, Ratna K., Hurez, Vincent J., Bahar, Rumana, Kious, Mark J., Livi, Carolina B., Wall, Shawna R., Chen, Lieping, Zhang, Bin, Shin, Tahiro, Curiel, Tyler J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244840/
https://ncbi.nlm.nih.gov/pubmed/20686128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000496
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