Clinical and Virologic Response to Episodic Acyclovir for Genital Ulcers among HIV-1 Seronegative, HSV-2 Seropositive African Women: A Randomized, Placebo-Controlled Trial

In a randomized trial among African women with recurrent genital herpes, episodic acyclovir therapy resulted in modestly greater likelihood of lesion healing (HR=1.48, p=0.098; mean 5.1 vs. 6.0 days) and cessation of HSV shedding (HR=1.88, p=0.008; mean 3.0 vs. 5.0 days) compared with placebo, simil...

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Autors principals: Baeten, Jared M., Reid, Stewart E., Delany-Moretlwe, Sinead, Hughes, James P., Wang, Richard S., Wilcox, Ellen, Limbada, Mohammed, Akpomiemie, Godspower, Corey, Lawrence, Wald, Anna, Celum, Connie
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244838/
https://ncbi.nlm.nih.gov/pubmed/22183840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/OLQ.0b013e31823b50c6
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